2020/11/25

Question Box Digest Part 10 -ED (Erectile Dysfunction/Erectile Dysfunction) Medicine-

I'm Maezawa, who often answers questions in the official universe anonymous question box.

This time, I tried to pick up the following questions.

I am a male member. I have a question for all the respondents who use ED medicine, how do you judge the appropriate amount that suits you?Depending on your physical condition, it may be difficult to work with the general amount that appears on the clinic or the web where you are prescribed.Is it okay to start with the standard small amount and gradually increase it?Thank you.

When I looked it up
viagra, cialis, levitra
There seems to be.

Viagrais a product of Pfizer Inc., headquartered in the United States.
It is the world's first commercialized ED treatment drug that is effective for ED (erectile dysfunction).
The active ingredients are sildenafil,Viagra” are trademarks owned by Pfizer.

After that, in October 2016, Pfizer launched a film-type product that dissolves on the tongue and is taken in Japan.Viagra(viagra OD film) are also on sale.

Duration of action: 25mg/4 hours, 50mg/5 hours
How to take: 1 hour before sexual activity
Drugs contraindicated for concomitant use: nitrates and NO donors, sGC stimulants, grapefruit
Effect of food: Yes (Effect decreases after eating)
Time to peak plasma concentration: 0.9±0.4 hours
Elimination half-life: 3.31±0.81 hours

ViagraAccording to the results of the experiment, drinking one hour before the act
The effect is strong around 3 hours (2.5 to 4.12 hours)
It is a feeling.

LevitraIt seems to be the drug that was born after Viagra as an ED (erectile dysfunction) drug.
It is manufactured and sold by Bayer Yakuhin, a pharmaceutical company headquartered in Germany, which is famous for the development of aspirin, and the active ingredient is "vardenafil".
"Levitra” is a registered trademark owned by Bayer Yakuhin.

It seems to be characterized by its fast-acting properties because it is more soluble in water than Viagra.

Duration of action: 10mg/5 hours, 20mg/7-9 hours
How to take: 1 hour before sexual activity (30 minutes before if fasting)
Features: Immediate effect
Contraindicated drugs: nitrates and NO donors, sGC stimulants, antiviral drugs (HIV drugs), oral antifungal drugs, antiarrhythmic drugs, grapefruit
Effects of diet: Low (low-fat diet up to 700 kcal)
Time to reach peak plasma concentration: 0.75 (0.50-1.00) hours
Elimination half-life: 3.98 hours (20mg)

LevitraConsidering the results of the experiment, drinking 45 minutes before the act
Strong effect for about 4 hours
It is a feeling.

 

CialisDeveloped by Eli Lilly & Co., Inc. in the United States, it is a saleta ED treatment drug that is available in 5 types: [10mg] [20mg] [3mg] depending on the content of the active ingredient tadalafil.
It is also called the "weekend pill" because if taken on Friday night, it lasts for a long time (up to 36 hours) until Sunday afternoon.

The biggest feature is the conventional ED treatment drugViagra-LevitraUnlikeEfficacy up to 36 hours after administration (20 mg dose)is recognized andIt seems to be characterized by not being affected by food once it is absorbed into the body.
It seems that many people choose this drug because it is the least affected by food among ED treatment drugs, and in August 2013It holds the number one share in the global market.

Duration of action: 10mg/20-24 hours, 20mg/30-36 hours
How to take: 1 hour before sexual activity (recommended on an empty stomach 3 hours before)
Features: long acting
Contraindicated drugs: nitrates and NO donors, sGC stimulants, grapefruit
Dietary effects: very unsusceptible

 

CialisHowever, based on various information on the Internet and when receiving prescriptions at hospitals, doctors have said that food has no effect. It seems that there are many people who say that

In fact, it seems that food has an effect.
In fact, after eatingCialisThere is also a story that many people say that it did not work when I took it, but it was effective when I took it on an empty stomach.

When it first went on sale, the manufacturer, Eli Lilly, stated in its documentation that food had no effect up to 800 kcal. (Currently, it seems that there are no documents stating the condition of up to 800 kcal, probably because they want to emphasize that "there is no food effect.")
Therefore, it seems better to think that it is still up to 800 kcal that is not affected by meals.

And basically, it seems that ED drugs should be taken on an empty stomach.

For reference, as an example of specific dosing timing
For example, if you eat from 19:21 to 22:1 and have sex from 18:XNUMX, it will be at XNUMX:XNUMX, one hour before the meal.CialisIf you take a tablet, the drug will be absorbed into your body to some extent at the time of the meal at 19:XNUMX, so it seems that you can draw out the effect rather than taking it immediately after the meal.

By the way,CialisLooking at the experimental results of
Time to peak plasma concentration is 3 hours
Elimination half-life: 14.4 hours
That's why I feel like it's best to drink 3 hours before the act.
I think that the effect will be strong until 14.4 hours later.

 

This is a rough outline, but it was the difference between ED drugs.

Considering the above resultsUniverseThe first setting of is to eat
Viagra, which is affected by food and becomes ineffective, is out of the candidates, and it seems better to choose Levitra or Cialis.

If anything, it seems that you can take it after getting a woman's OKLevitraseems to be good (because you don't have to take it if the woman refuses),
from the respondentsCialisSince there was also a voice that was takingCialisIt seems to be good to take 1 hour before meals.

Come to think of it, there was a man who once said that he doesn't eat when he's setting up because he loses his libido when he eats.

The above is just an amateur's research, so please ask your doctor before using it.

 

 

Author of this article

When someone talks about love, they say, "Stop laughing! If someone like you talks about love or tears, love will become unclean." ), and so many times!" When asked if he was not afraid, he answered, "Huh, I'm afraid. That's ridiculous. Fear, suffering, pain, sadness, despair. Such weak emotions. I threw it away a long time ago.The only thing left for me is the heart of Asura, which fell into the hell of battle.Therefore, I will continue to fight.Until the moment my life runs out!"When I'm in a pinch, I say, "Not yet, it's not over yet." The man who said... 

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